Notice: Function _load_textdomain_just_in_time was called incorrectly. Translation loading for the wordpress-seo domain was triggered too early. This is usually an indicator for some code in the plugin or theme running too early. Translations should be loaded at the init action or later. Please see Debugging in WordPress for more information. (This message was added in version 6.7.0.) in /var/www/html/wp-includes/functions.php on line 6260 CoQ10 - Nutraceuticals World

What are you searching for?

Sign in
Research

CoQ10

Author Image

By: Sean Moloughney

Editor, Nutraceuticals World

Indication: Parkinson’s disease


Source: Arch Neurol, May 14, 2007 [Epub ahead of print]

Research:
The aim of this study was to determine whether nanoparticular CoQ10 is safe and displays symptomatic effects in patients with mid-stage Parkinson’s disease without motor fluctuations. In this multi-center, randomized, double-blind, placebo-controlled trial 131 patients were given either 300 mg of CoQ10 or placebo for a period of three months—a total of 106 subjects completed the trial. The subjects underwent evaluation with the Unified Parkinson’s Disease Rating Scale (UPDRS) at each visit on a monthly basis. The primary outcome variable was the change of the sum score of the UPDRS parts II and III between baseline and 3-month visits.

Results:
Statistical analysis according to the stratification did not result in significant changes of the primary outcome variable. No secondary outcome measure showed a significant change between the placebo group and the CoQ10 group. The frequency and quality of adverse events were similar in both treatment groups. Although nanoparticular CoQ10 at a dosage of 300 mg per day is safe and well tolerated and leads to plasma levels similar to 1200 mg per day of standard formulations, add-on CoQ10 does not display symptomatic effects in mid-stage Parkinson’s disease.

Add us as a preferred source on Google

Get the latest Nutraceuticals World news, insights and analysis in your Google Search and AI experiences.

Add Nutraceuticals World as a preferred source on Google (opens in a new tab)

Keep Up With Our Content. Subscribe To Nutraceuticals World Newsletters